As a senior at Duke University in 2010, Dr. Quinn Wang was simply Quinn, an undergraduate English major on the pre-med track, wondering how to combine her love for medicine with her love for English. This is how her senior thesis was conceived – Through the Lens of Medicine: Landscapes of Violence in Cormac McCarthy’s Blood Meridian (1985), All the Pretty Horses (1992), and No Country for Old Men (2005) – which ended up winning the English department’s award for “Most Original Honors Thesis.”
Dr. Quinn Wang
Fast forward 12 years, and Wang can now call herself a double Dukie, having completed medical school here. She went on to complete ophthalmology residency at UCSF and this past Saturday, November 5, came back to her alma mater as part of the Duke Medical Ethics Journal’s Medicine, Humanities, and Business celebration to talk to an eager audience at Schiciano Auditorium about her path from Duke until now.
She began her story during the infamous year of 2020, when she was forced to stop seeing patients at her private practice in California’s Bay Area due to COVID-19. Restless and anxious about how her patients were doing, she tried to keep up with them as best she could, but of course there were limitations. And then, a few months in, one of her patients went blind.
This tragic moment sparked a frustrating realization by Wang that in the tech capital of the world – San Francisco – there was still no good way to test people’s eyesight from home to prevent what should have been preventable. She decided to put together something herself, guided by the one question she thought was most important to answer until COVID-19 abated and people could come into clinics again – “how do we make sure people don’t go blind?”
Wang took common visual eye-testing tools used in clinics, and with some simple Photoshop editing and a little bit of code, turned them into a series of easy multiple-choice questions that could be answered from home. This simple but powerful transformation turned into Quadrant Eye, a start-up she co-founded with software engineer Kristine Hara.
A common visual tool used to test eyesight is the Snellen chart
The Quadrant Eye journey has taken her from running a private practice as an ophthalmologist to taking the plunge into business by applying to and getting selected for Y Combinator, which calls itself a “graduate school for startups”. YC invests $500,000 into a selection of early-stage startups twice a year. Then, for three intense months, they provide support to get startups off the ground and in good shape to present to investors for funding. At YC, Hara worked on turning Quadrant Eye into an app, and Wang renewed hundreds of prescriptions.
Quadrant Eye
Ultimately, though, the most significant place Quadrant Eye has led Wang to is a journey of self-mastery that applies to any human endeavor, from building a startup to doing research to just getting up every morning. As she describes, startup life entails always learning new things and always messing up – which, for someone who professes that “I don’t like to do things I’m not good at” – can be challenging. She candidly admitted that she, like everyone, has bad days, when sometimes all she can do is throw in the towel and end work early. “I have more doubts than I care to admit,” Wang says, but at the end of the day, “we’re all climbing our own mountains”. Pushing through requires “superhuman effort” but it’s worth it.
And as for that English thesis? Wang describes how Quadrant Eye’s very first investor – “let’s call him Charlie” – asked her all the requisite questions investors ask early-stage startups (think Shark Tank). But he also asked her for something non-traditional – all fifty or so pages of her undergraduate honors thesis she had written ten years back. Apparently, he had seen a mention of it on LinkedIn and was intrigued. A few weeks later, Wang received a phone call that he was interested in investing – and he admitted that her thesis had played a part. To him, the uniqueness and quality of her thesis showed that Wang could problem-solve, communicate well, and think creatively, and Wang herself agrees. “My English thesis showed me that I can do hard things,” she said, and if Quadrant Eye is any indication, clearly, she can.
“After COVID-19,” senior Cynthia Dong (T’23) remarks, “so much of what was wrong with the medical system became visible.”
Duke undergraduate Cynthia Dong, Class of 2023
This realization sparked an interest in how health policy could be used to shape health outcomes. Dong, who is pursuing a self-designed Program II major in Health Disparities: Causes and Policy Solutions, is a Margolis Scholar in Health Policy and Management. Her main research focus is telehealth and inequitable access to healthcare. Her team looks at patient experiences with telehealth, and where user experience can be improved. In fact, she’s now doing her thesis as an offshoot of this work, researching how telehealth can be used to increase access to healthcare for postpartum depression.
Presenting research on telehealth
In addition to her health policy work, however, Dong also works as a research assistant in the neurobiology lab of Dr. Anne West, and her particular focus is on the transcription mechanism of the protein BDNF, or brain-derived neurotrophic factor.
While lab research can be clearly visualized by most people (think pipettes, rows of benches littered with bottles and plastic tubes, blue rubber gloves everywhere), health policy research is perhaps a little more abstract. When asked what the process of research through Margolis is like, Dong says that “it’s not team-based or individual – it’s a lot of both.” This looks like individual research on specific topics, talking to different stakeholder groups and people with certain expertise, and then convening for weekly team meetings.
With other Margolis Scholars
For Dong, research has been invaluable in teaching her to apply knowledge to something tangible. Doing that, you’re often “forced to understand that not everything is in my control.” But on the flip side, research can also be frustrating for her because so much of it is uncertain. “Will your paper get published? Is what you’re doing relevant to the research community? Will people invest in you?”
In that vein, research has humbled her a lot. “What it means to try to solve a societal problem is that it’s not always easy, you have to break it down into chunks, and even those chunks can be hard to solve.”
After graduation, Dong plans on taking a couple of gap years to be with family and scribe before ultimately pursuing an MD-MPH. Because research can be such a long, arduous process, she says that “It took me a long time to realize that the work we do matters.” In the future, though, she anticipates that her research through Margolis will directly inform her MPH studies, and that “with the skills I’ve learned, I can help create good policy that can address the issues at hand.”
What brings seniors Deney Li and Amber Fu together? Aside from a penchant for photoshoots (keep scrolling) and neurobiology, both of them are student research assistants at the lab of Dr. Andrew West, which is researching the mechanisms underlying Parkinson’s in order to develop therapeutics to block disease progression. Ahead lie insights on their lab work, their lab camaraderie, and even some wisdom on life.
(Interview edited for clarity. Author notes in italics.)
What are you guys studying here at Duke? What brought you to the West lab?
DL: I am a biology and psychology double major, with a pharmacology concentration. I started working at a lab spring semester of freshman year that focused on microbial and environmental science, but that made me realize that microbiology wasn’t really for me. I’ve always known I wanted to try something in pharmaceutics and translational medicine, so I transitioned to a new lab in the middle of COVID, which was the West lab. The focus of the West lab is neurobiology and neuropharmacology, and looking back it feels like fate that my interests lined up so well!
Deney Li
AF: I am majoring in neuroscience with minors in philosophy and chemistry, on the pre-med track. I knew I wanted to get into research at Duke because I had done research in high school and liked it. I started at the same time as Deney – we individually cold-emailed at the same time too, in the fall! I was always interested in neuroscience but wasn’t pre-med at the time. A friend in club basketball said her lab was looking for people, and the lab was focused on neurobiology – which ended up being the West lab!
Amber Fu
What projects are you working on in lab?
DL: My work mainly involves immunoassays that test for Parkinson’s biomarkers. My postdoc is Yuan Yuan, and we’re looking at four drugs that are kinase inhibitors (kinases are enzymes that phosphorylate other proteins in the body, which turns them either on or off). We administer these drugs to mice and rats, and look at LRRK2, Rab10 and phosphorylated Rab10 protein levels in serum at different time points after administration.These protein levels are important and indicative because more progressive forms of Parkinson’s are related to higher levels of these proteins.
AF: For the past couple of years, I’ve been working under Zhiyong Liu (a postdoc in the lab). There are multiple factors affecting Parkinson’s, and different labs ones study different factors. The West lab largely studies genetic factors, but what we’re doing is unique for the lab. There’s been a lot of research on how nanoplastics can go past the blood-brain barrier, so we are studying how this relates to mechanisms involved in Parkinson’s disease. Nanoplastics can catalyze alpha-synuclein aggregation, which is a hallmark of the disease. Specifically, my project is trying to make our own polystyrene nanoplastics that are realistic to inject into animal models.
What I’m doing is totally different from Deney – I’m studying the mechanisms surrounding Parkinson’s, Deney is more about drug and treatments – but that’s what’s cool about this lab – there are so many different people, all studying different things but coming together to elucidate Parkinson’s.
Another important project
How much time do you spend in lab?
DL: I’m in lab Mondays, Wednesdays, and Fridays from 9 to 6. All my classes are on Tuesdays and Thursdays!
AF: I’m usually in lab Tuesdays and Thursdays from 12 to 4, Fridays from 9 to 11:45, and then whenever else I need to be.
Describe lab life in three words:
DL: Unexpected growth (can I just do two)?
AF: Rewarding, stimulating, eye-opening.
Lab life also entails goats and pumpkins
What’s one thing you like about lab work and one thing you hate?
DL: What I like about lab work is being able to trouble-shoot because it’s so satisfying. If I’m working on a big project, and a problem comes up, that forces me to be flexible and think on my toes. I have to utilize all the soft skills and thinking capabilities I’ve acquired in my 21 years of life and then apply them to what’s happening to the project. The adrenaline rush is fun! Something I don’t like is that there’s lots of uncertainty when it comes to lab work. It’s frustrating to not be able to solve all problems.
AF: I like how I’ve been able to learn so many technical skills, like cryosectioning. At first you think they’re repetitive, but they’re essential to doing experiments. A process may look easy, but there are technical things like how you hold your hand when you pipette that can make a difference in your results. Something I don’t like is how science can sometimes become people-centric and not focused on the quality of research. A lab is like a business – you have to be making money, getting your grants in – and while that’s life it’s also frustrating.
What do you want to do in the future post-Duke? How has research informed that?
DL: I want to do a Ph.D. in neuropharmacology. I’m really interested in research on neurodegeneration but also have been reading a lot about addiction. So I’ll either apply to graduate school this year or next year. My ultimate goal would be to get into the biotech startup sphere, but that’s more of a 30-years-down-the-road goal! Being in this lab has taught me a lot about the pros and cons of research, which I’m thankful for. Lab contradicts with my personality in some ways– I’m very spontaneous and flexible, but lab requires a schedule and regularity, and I like the fact that I’ve grown because of that.
AF: The future is so uncertain! I am currently pre-med, but want to take gap years, and I’m not quite sure what I want to do with them. Best case scenario is I go to London and study bioethics and the philosophy of medicine, which are two things I’m really interested in. They both influence how I think about science, medicine, and research in general. After medical school, though, I have been thinking a lot about doing palliative care. So if London doesn’t work out, I want to maybe work in hospice, and definitely wouldn’t be opposed to doing more research – but eventually, medical school.
What’s one thing about yourself right now that your younger, first-year self would be surprised to know?
DL: How well I take care of myself. I usually sleep eight hours a day, wake up to meditate in the mornings most days, listen to my podcasts… freshman-year-Deney survived on two hours of sleep and Redbull.
AF: Freshman year I had tons of expectations for myself and met them, and now I’m meeting my expectations less and less. Maybe that’s because I’m pushing myself in my expectations, or maybe because I’ve learned not to push myself that much in achieving them. I don’t necessarily sleep eight hours and meditate, but I am a little nicer to myself than I used to be, although I’m still working on it. Also, I didn’t face big failures before freshman year, but I’ve faced more now, and life is still okay. I’ve learned to believe that things work out.
This is part one of a two-part series; next week we will dive into the nitty-gritty of biblical research, but for now, we’re focusing on what biblical research is and why it matters.
To the uninitiated, “biblical research” might not conjure up images of dancing, or analyzing films, or studying engineering. But meet Maximillion Whelan. A third-year M.Div. student at Duke, Whelan runs a website for film aficionados focusing on analyzing movie scenes and was recently published in Quarterly Review of Film and Video for an article on theology and film. He notes: “Biblical research sheds light on how everyday activities effectively shape history and are also shaped by history. By “zooming in,” delving into the details and contexts, biblical research enables us to simultaneously “zoom out” – to see what things we are taking for granted, where our readings have led us, and how we take our readings into other spheres of life.”
Image courtesy of Nicole Kallson (as part of her course Introduction to Theology and the Arts)
Or take Divinity School student Nicole Kallson. She is pursuing a Master’s of Theological Studies with a Certificate in Theology and the Arts.
“As a theologian and dancer, I use my background in dance to assist my understanding of the Bible.” Kallson explains. “I tend to focus on ideas of embodiment, beauty, and inter- and intra- personal relationships.”
Both students—along with countless other Blue Devils and other mascot identities—use their studies as a lens through which to examine themselves and their passions. And isn’t that what we emphasize so clearly at Duke—the interdisciplinary, interpersonal, interfaith, international, interwoven identities of people, places, and things? Is that not what research is all about in the end? Perhaps the purpose of biblical research is not as foreign to us as we may think at first.
Degree-seekers may come from expertise in literature, classical studies, practical faith, or other backgrounds that may easily come to mind. But they also come from natural sciences, physical sciences, political science, art and media studies, creative writing, engineering, medicine, sociology, public policy, economics, and so much more. And each of these students is applying their research and understanding of the Bible to their understanding of the world at large, seeking to become better, more intentional academics in the process.
The new Dean of Duke Divinity School was born and raised in Puerto Rico; he has prayed with Pope Francis and presented him with writings on interfaith dialogues. He also has Bachelor’s and Master’s degrees in mechanical engineering.
“It might seem odd to have a series focused on the Bible as a banned book, given that it’s the most polished book in history,” he opened. He gave an example further; for a time in recent Guatemalan history, possession of the Bible was persecuted as a means of targeting perceived Communist empathizers. Even within Christain communities, he explains, there has been discourse among devotees of certain translations and versions—not all of them amenable.
The event also featured Brent Strawn of the Duke Divinity School and Jennifer Knust from Trinity College of Arts & Sciences Department of Religious Studies.
Jennifer Knust during the Forever Learning Institute’s Policing Pages presentation on the Bible
“The survival of the New Testament as a text and a collection is a theological and practical achievement,” noted Knust. “It is repeatedly refreshed in response to new circumstances, even as remains of past approaches continue to shape what can happen next.”
It is because of the differing opinions of so many people over such a long time that we have different faiths, and biblical research uses the lens of Christianity to evaluate that phenomenon.
Knust continues: “Today we know that there are over 5,000 manuscript copies of the New Testament, none of which are identical in every particular.”
She herself was a member of the board of the New Revised Standard Version Updated Edition—the most recent scholarly translation of the Bible, published in 2021. She elaborated on her feelings on the dynamics and fluidity of the text, describing a constant push and pull of desire and tradition. Perhaps researchers, in the present, past, or future, may desire to change words, meanings, or uses of the Bible, but they are contradicted by a tradition dictated by the populous.
Biblical research seeks to answer questions about the Bible— and by extension, the fruitfulness of humanity. The sustainability of religious texts of all kinds is a testament (pun intended) to the success of human minds compounded over thousands of years.
A 1611 copy of the Authorized Version Knustuses as an example of different Protestant translations.
On this PeopleMover-style tour of biblical research, I hope we’ve taken away some key points:
Firstly, the work of many biblical researchers is deeply personal. We’ve discovered through this that the work of any researcher in any field has the potential to be deeply personal.
Additionally, we learned that the interdisciplinary reach of biblical studies works inversely; students may turn to biblical research from other subjects to enhance their work, or they may even turn to other subjects to enhance their work in biblical research.
And finally, we arrive at our destination; next week we’ll talk more in-depth about what biblical research entails and meet some key players in those conversations.
Young people have the power to generate change, whether they know it or not.
At least that was the sentiment expressed by the Director of Polling at the Harvard Institute of Politics, John Della Volpe at a seminar earlier this month. A leading authority on the intersection of young Americans and political influence, Della Volpe discussed the key role Generation Z will play in the 2022 and 2024 elections.
But does Generation Z really have what it takes to change the course of American politics?
“We spend a lot of time talking about Gen Z, and not enough time talking to you,” Della Volpe began as he addressed a crowd of young Duke students. “This is one of the rare occasions where I’m going to be doing most of the talking rather than most of the listening.”
Stanford Researcher Roberta Katz describes Generation Z — those born between 1997 and 2012 — as a highly collaborative cohort with a pragmatic attitude about generational issues like political engagement.
Exit Polls from NBC reveal that Gen Z was responsible for more than 9% of total votes in the 2020 presidential election, with that number only expected to grow. In Georgia and Arizona, young voters turned out to be critical for President Joe Biden’s victory, Della Volpe said.
Exit Polls From NBC show 2020 total votes for Biden compared to Trump, with Generation Z voting for Biden two-to-one.
He urges Gen Z to “remind elected officials that you did change things and that you will continue changing things.” Della Volpe predicts that Gen Z’s choices will also be crucial in the 2022 midterms.
Occupy Wall Street, the election of Trump, the Parkland Shooting, Greta Thunberg, and the killing of George Floyd were five events that Della Volpe believed were crucial in shaping this trajectory, as well as Gen Z’s political view as a whole.
“We have to look collectively at what you as a cohort saw and how that’s affecting you. In fact, I think that’s a far better way to think about our politics than what state you are in.”
The way parents think about bills and taxes, the way that weighs on your shoulders, that’s the way we think about living and dying.
Gen Z woman in conversation with John Della Volpe
“No generation in 70 years has dealt with more chaos, more trauma, more struggle before your brain is even fully developed,” Della Volpe asserted. He maintains that Generation Z is dealing with extremely complex issues much earlier than other generations.
Research from the American Psychological Association bears this out, indicating that Gen Zers are currently the most stressed demographic of people in the United States. They are also significantly more likely to rate their mental health as poor in comparison to other generations.
“I’m very cognizant of not putting any more pressure on you,” said Della Volpe. “You are already doing such a good job of managing yourselves and managing your situation.”
John Della Volpe’s book, published earlier this year.
Generation Z is managing so well, in fact, that Della Volpe argues they are essential to the success of US politics moving forward. In his book ‘Fight: How Generation Z is Channeling Their Fear and Passion to Save America,’ Della Volpe argues that the challenges unique to Gen Z prepare them to take control of their future in this nation.
Thanks to Della Volpe the answer is overwhelmingly clear: Gen Z does have what it takes to turn this nation around. So get out there and vote!
In recognition of the 50th anniversary of Title IX, which was intended to make sex discrimination in education illegal, a panel of Duke women met on Thursday, September 29 to talk about whether Title IX could change STEM, (Science Technology, Engineering and Math). Unfortunately, the answer was not simple.
But just through the sharing of the statistics relevant to this problem, the stories, and their solutions, one could start to understand the depth of this problem. One takeaway was that all women in STEM, whether they be student, professor, or director, have faced gender discrimination.
The student panelists after a successful forum
Down to the Statistics:
Dr. Sherryl Broverman, a Duke professor of the practice in biology and global health, gave the audience an overview. Of all of Duke’s regular ranked, tenured-track faculty, only 30% are women. In contrast, women make up 60% of the non-tenure track faculty. Dr. Broverman said men are promoted in Duke at a higher frequency. This is especially seen with the associate professor title because, on average, men are associate professors for 4 to 5 years; whereas women are associate professors for up to 9 years.
To give an example, senior Nasya Bernard-Lucien, a student panelist who studied Biomedical Engineering and then Neuroscience informed me that she has had a total of two women professors in her entire STEM career. This is a common pattern here at Duke because taking a STEM class that has a woman professor is as rare as finding a non-stressed Duke student.
Dr. Kisha Daniels (left) and Dr. Whitney McCoy (right)
The Beginning of a Girl’s Career in STEM
This disproportionate demographic of women professors in STEM is not a new occurrence with Duke or the rest of the world because the disproportion of women in STEM can be seen as early as middle school. Two of the student panelists noted that during their middle school career, they were not chosen to join an honors STEM program and had to push their school’s administration when they asked to take more advanced STEM classes.
Dr. Kisha Daniels, an associate professor of the practice in education said on a faculty panel that one of her daughters was asked by her male peers, “what are you doing here?” when she attended her middle school’s honors math class. Gender discrimination in STEM begins in early childhood, and it extends its reach as long as women continue to be in a STEM field, and that is particularly evident here at Duke.
Women in STEM at Duke
Dr. Sherryl Broverman
The last panel of the Title IX @ 50 event was the student panel which consisted of undergraduate and graduate students. Even though they were all from different backgrounds, all acknowledged the gender disparity within STEM classes.
Student Bentley Choi said she was introduced to this experience of gender discrimination when she first arrived at Duke from South Korea. She noted how she was uncomfortable and how it was hard to ask for help while being one of the few women in her physics class. One would have hoped that Duke would provide a more welcoming environment to her, but that is not the case, and it is also not an isolated incident. Across the panel, all of the women have experienced discomfort in their STEM classes due to being one of the few girls in there.
The Future of Title IX
How can Title IX change these issues? Right now, Title IX and STEM are not as connected as they need to be; in fact, Title IX, in the past, has been used to attack programs created to remedy the gender disparity in STEM. So, before Title IX can change STEM, it needs to change itself.
Title IX needs to address that this problem is a systemic issue and not a standalone occurrence. However, for this change to happen, Dr. Whitney McCoy, a research scientist in Child and Family Policy, said it perfectly, “we need people of all backgrounds to voice the same opinion to create policy change.”
So, talk to your peers about this issue because the more people who understand this situation, the chances of creating a change increases. The last thing that needs to occur is that 50 years in the future, there will be similar panels like this one that talk about this very issue, and there are no panels that talk about how we, in the present, fixed it.
Dhruv Rungta, a member of the Wild Ones club, with a ring-necked snake during a herpetology walk with Dr. Nicki Cagle in the Duke Forest. Upper left: Dr. Nicki Cagle holding a ring-necked snake. Photo by Montana Lee, another Wild Ones member.
On a sunny Friday in September, Dr. Nicki Cagle led a herpetology walk in the Duke Forest with the Wild Ones. The Wild Ones is an undergraduate club focused on increasing appreciation for the natural world through professor-led outings. Herpetology is the study of reptiles and amphibians.
Dr. Cagle is a senior lecturer in the Nicholas School of the Environment at Duke and the Associate Dean of Diversity, Equity, and Inclusion. Along with teaching courses on environmental education and natural history, she is also the science advisor for a citizen science project focused on reptiles and amphibians, or herpetofauna, in the Duke Forest. Volunteers monitor predetermined sites in the Duke Forest and collect data on the reptiles and amphibians they find.
“We get a sense of abundance, seasonality… and how the landscape is affecting what we’re seeing,” Dr. Cagle says. There is evidence that herp populations in the Duke Forest and elsewhere are decreasing.
Dr. Nicki Cagle flipping over a cover board with members of the Wild Ones. The cover boards are used to monitor reptiles and amphibians for a citizen science project in the Duke Forest.
The project relies on transects, “a sampling design… where you have a sampling spot at various intervals” along a line of a predetermined length. In this case, the sampling spots are “traps” meant to attract reptiles and amphibians without harming them. Each site has a large board lying on the ground. “Different herps are more likely to be found under different objects,” Dr. Cagle explains, so the project uses both wooden and metal cover boards.
But why would snakes and other herps want to hide under cover boards, anyway? Reptiles and amphibians are “cold-blooded” animals, or ectotherms. They can’t regulate their own body temperature, so they have to rely on their environment for thermoregulation. Snakes might sun themselves on a rock on cold days, for instance, or hide under a conveniently placed wooden board to escape the heat.
Salamanders that use the cover boards might be attracted to the moist environment, while “snakes will tend to go under cover boards either to hide — like if they’re about to molt and they’re more vulnerable — to look for prey, or just to maintain the proper temperature,” Dr. Cagle says.
Citizen scientists typically check the boards once a week and not more than twice a week. Volunteers have to avoid checking the traps too often because of a phenomenon called “trap shyness,” where animals might start avoiding the traps because they’ve learned to associate them with pesky humans flipping the boards over and exposing their otherwise cozy resting places. By checking the traps less frequently, scientists can reduce the likelihood of that and minimize disturbance to the animals they’re studying.
The first snake we saw was a redbelly snake (Storeria occipitomaculata), dark above with a pink stomach.
Dr. Cagle gave the Wild Ones a behind-the-scenes tour of some of the cover boards. Using a special, hooked tool conveniently stashed in a PVC pipe next to the first cover board, we flipped each board over and looked carefully underneath it for slithery movements. We didn’t find any under the first several cover boards.
But then, under a large sheet of metal, we saw a tiny snake squirming around in the leaf litter. There was a collective intake of breath and exclamations of “snake!”
Dr. Cagle captured it and held it carefully in her hands. Snakes, especially snakes as young as this one, can be all too easily crushed. We gathered around to look more closely at the baby snake, a species with the adorable name “worm snake.” It was dark above with a strikingly pink underside. The pink belly is a key field mark of worm snakes. Earth snakes are also found around here and look similar, but they tend to have tan bellies.
After a minute or two, the worm snake made a successful bid for freedom and wriggled back under the board, disappearing from sight almost immediately.
Crossing over a dry “intermittent stream,” which Dr. Cagle describes as “the running-water equivalent of a vernal pool.” A vernal pool is a temporary wetland that is dry for much of the year.
Some of the cover boards revealed other animals as well. We found a caterpillar chrysalis attached to one and several holes — probably made by small mammals — under another.
Whatever made the holes, we can safely assume it wasn’t a snake. According to Dr. Cagle, the term “snakehole” is misleading. Most snakes don’t make their own holes, though some of them do use existing holes made by other animals. One exception is the bull snake, which is known for digging.
We found a young five-lined skink sunning itself on top of one of the metal cover boards. (Thermoregulation!) Juvenile five-lined skinks are colloquially known as blue-tailed skinks, but the name is somewhat misleading — the adults don’t have blue tails at all.
The snakes we were looking for, meanwhile, were often elusive. Some vanished under the leaf litter before we could catch them. Sometimes it was hard to tell whether we were even looking at a snake at all.
“What are you?” Dr. Cagle muttered at one point, crouching down to get a better look at what was either a stick-esque snake or a snake-esque stick. “Are you an animal? Or are you just a wet something?” (Just a wet something, it turned out.)
The Duke Forest is a valuable community resource with a complicated history. “We know that slavery was practiced on at least four properties” in the Duke Forest, Dr. Cagle says, and the forest is located on the traditional hunting grounds of several indigenous peoples. Today, the Duke Forest is used for research, recreation, timber management, and wildlife management and conservation.
Later on, we found at least three young ring-necked snakes (Diadophis punctatus) under different cover boards. One of them was particularly cooperative, so we passed it around the group. (“All snakes can bite,” Dr. Cagle reminded us, but “some have the tendency to bite less,” and this species “has the tendency not to bite.”) Its small, lithe body was surprisingly strong. The little snake wrapped tightly around one of my fingers and seemed content to chill there. A living, breathing, reptilian ring. That was definitely a highlight of my day.
The faint, dark line on this ring-necked snake’s underside (on the bottom of the loop) is the anal vent. Everything below that point (farther from the head) is considered the official tail of a snake.
If you’ve ever wondered if snakes have tails, the answer is yes. The official cut-off point, Dr. Cagle says, is the anal vent. Everything below that is tail. In between flipping over cover boards and admiring young snakes, we learned about other herps. Near the beginning of our walk, someone asked what the difference is between a newt and a salamander.
“A newt is a type of salamander,” Dr. Cagle says, “but newts have an unusual life cycle where they spend part of their life cycle on land… and that is called their eft phase.” As adults, they return to the water to breed.
We learned that copperheads “tend to be fatter-bodied for their length” and that spotted salamanders cross forest roads in large numbers on warm, rainy nights in early spring when they return to wetlands to breed.
Students holding a ring-necked snake. Above: Kelsey Goldwein (left), Gurnoor Majhail (one of the co-presidents of the Wild Ones), and Simran Sokhi (background on right). Below: Emily Courson (left) and Barron Brothers.
Perhaps the most interesting herp fact of the day came near the end of our walk when one of the students asked how you can tell the sex of a snake. Apparently there are two ways. You can measure a snake’s tail (males usually have longer tails), or you can insert a metal probe, blunted at the end, into a snake’s anal vent. Scientists can determine the sex of the snake by how deep the probe goes. It goes farther into the anal vent if the snake is a male. Why is that? Because male snakes have hemipenes — not two penises, exactly, but “an analogous structure that allows the probe to slide between the two and go farther” than it would in a female snake. The more you know…
Looking for snakes on a herpetology outing with Dr. Cagle and the Wild Ones. Photograph by Gurnoor Majhail.
Disclaimer: Handling wild snakes may result in snake bites. It can also be stressful to the snakes. Furthermore, some snakes in this area are venomous, and it’s probably best to familiarize yourself with those before getting close to snakes rather than afterward. Snakes are amazing, but please observe wildlife safely and responsibly.
Bonus snake! I saw this adorable fellow on the Duke Campus and thought it was an earthworm at first. Dr. Cagle thinks it might be a rough earth snake. I did not check to see if it had a tan belly.
If you asked my eight-year-old self what I wanted to be when I grew up, the answer would have been, resoundingly, “an inventor!” It was around this time that I also decided, with surprising assuredness for a shy second grader, that I would one day build a saltwater-powered car.
I must have heard the idea somewhere, although to this day I don’t quite recall where. Perhaps it was a story on the radio. NPR was a constant background noise in the basement where I spent countless hours playing and tinkering alongside my father in his hobby shop. Or maybe it was buried somewhere in a book or science magazine. They were often stacked in neat piles, filling bookcases in many corners of our house. It also could have floated across the dinner table in conversations between my parents and older siblings. Everyday talk of high school biology and current events seemed light years out of the grasp of my eight-year-old brain.
Kyla Hunter, Duke Engineering 2023.
Regardless of where it came from, the idea stuck. Before I knew what it meant to conduct research or study engineering, I found myself charmed by novel ideas and drawn to the possibility of discovery. For some reason, this “car that runs on salt water” took shelter in my mind and secured itself as the perfect idea: an ingenious invention that was good for the planet. At the time, of course, I never thought about how this whimsical, far-fetched idea was fundamentally tied to my core interests and values. Now, however, as a 21-year-old senior studying mechanical engineering, passionate about renewable energy technology and protecting the planet, it all makes perfect sense.
My interest in engineering is, at its core, a love for creativity, combined with a desire to solve problems. A fondness for physics certainly helps too, but that came much later. As a child, the desire to practice creativity manifested primarily as a love for art. Some of my earliest childhood memories are toiling away at my little table in the corner of the living room, carefully sorting the crayons in my tin Crayola box. Today, I practice creativity in my critical thinking, brainstorming, and implementation of the iterative design process.
At an elementary school science fair, I presented my model V8 engine and explained how it worked. I was drawn to many different interests before I settled on engineering, but it’s clear that the passion was always there.
The other facet that drew me towards engineering, the desire to solve problems, evolved from an early love for nature and a passion for environmentalism. I remember seeing my grandparents’ devastated home in the aftermath of Hurricane Sandy, and the noticeable decline in pollinators to my mother’s garden. In high school, when I heard the term “environmental engineering,” it was the first time I realized such a field existed. I immediately felt the various pieces of my interests and values click together. There are many ways to be creative and to solve problems, but for me, the combination led down a path towards pursuing engineering.
An entry from my second-grade journal, declaring my dearly held beliefs. In many ways, nothing has changed (including my ability to spell).
Despite the way I’ve laid it out, this is not to say there was a linear path between latching onto an eccentric notion as an eight-year-old, and deciding to pursue my current career as a soon-to-be graduate. Looking back now, I can see the symbolism in this cornerstone of an idea. With hindsight, I recognize why it appealed to different facets of my just-blossoming identity, and the ways in which I returned to it over the next several years. However, this is what is bound to happen when you expose yourself to as many new ideas as possible: one (at least) will catch your attention. The point is not to latch onto the first idea you stumble upon and pursue it relentlessly. The point is to keep an open mind to all ideas – and pay careful attention to the ones that light up inside your brain. The ones that stick in the back of your mind, and continuously pop up at unsuspecting times.
One of my favorite serendipitous moments in life is when, soon after learning something new, that newfound idea pops up somewhere else. It’s like receiving an unexpected gift in the form of previously inaccessible appreciation. Imagine turning over a stone and happening to uncover an insect that you just spent all night studying. It feels purely by chance, but it’s not quite.
The more you expose yourself to new ideas, the more they will appear. You never know when a story you stumble across by accident will move you to action, or lead to something bigger. A magazine I stumbled across by chance led to a research topic of an entire semester. A book I read in high school came up in an interview I had last week. An idea I heard at eight years old about an eco-friendly car perhaps started a life-long captivation with science that led me to become an engineer. Our life is made up of decisions that are based on millions of data points, determined by our history, background, and the types of ideas we surround ourselves with daily.
As a blogger for the Duke Research Blog, my goal is to make it easier for more people to have more exposure to more ideas. Each new idea has the potential to build bridges, whether expanding to new fields, or building upon an existing network of knowledge. Expanding our realm of understanding allows for challenging perspectives and broadening understandings. These are not ideas for the sake of ideas, but for the larger goal of enabling meaningful connections with others.
When more people have access to more ideas, everyone benefits. However, there’s no denying that much of the research going on at Duke is very high-level, usually going unread by much of the student body. Other fascinating content goes unnoticed simply due to the busy lives of Duke students, and the sheer volume of exciting events. (If only we could all be multiple places at once.) My goal is to take ideas – whether overly intimidating or underappreciated—and present them in a way that is more accessible for anyone who is interested.
When I first heard of the idea of salt-water running cars, the idea was just that: an idea. The frenzy began in 2007 when John Kanzius, an American engineer, accidentally discovered how to “burn” salt water while attempting to research a cure for cancer. Today, the QUANT e-Sport Limousine is an all-electric sports car concept that uses an electrolyte flow cell, powered by salt water. It actually works, and was authorized for on-road testing in Germany a few years ago soon after its debut. It is many years from authorization, and it will likely be an even longer time before it is a viable option from an economic standpoint, but the progress is apparent.
Fifteen years since my infatuation with this idea, I can’t help but feel slightly emotionally connected to it. Humans grow up. Ideas do, too. I did not invent the first car that runs on salt water, but I am eternally grateful for every new idea that fuels my curiosity, shapes my values, and expands my current perspectives.
“My name is Meg Stalter I’m 5’7 I’m living in LA and a fun fact about me is something bad happened to my cousin.”
As made evident by her Twitter profile, my favorite comedian, Megan (“Meg”) Stalter, knows how to make an introduction. Stalter is best known (as far as I know) for her role in the HBO comedy “Hacks,” in which she plays Kayla (whoever that is).
I do not have a Twitter account and I have never seen the show. While we are talking about me, I will explain that I do not really watch TV, with the one exception of West Wing.
Since we are still talking about me, you should know that I fibbed. There are two exceptions. The other one is Grantchester, a Masterpiece Mystery about a hot priest who solves crime (but that was sort of a given, no?).
I share Stalter’s bio for a few reasons. For starters, it makes me smile, and sharing a smile is a tried-and-true way to score a friend (cha-ching!).
Meg Stalter once again proved her knack for making a first impression at her Emmy’s debut
On top of that, it is a good example of someone who knows how to make a first impression. I expect to have made a great impression by the time I finish this, but to ensure things got started on the right foot, hedging my bets if you will, I thought it best to leave the preamble to someone at the top of the trade.
Stalter’s bio also proves a simple point; it is not merely what you say that counts, but how you say it.
I am something of a sub-par reader. I love to read, it is just not my biggest strength (doesn’t mean it can’t be (growth mindset)! Just facing today’s facts). I don’t think I read enough as a child, so now I am slow and I usually fall asleep.
But I get by. I power through my class readings, I keep a book on my bedside table, and I get my news through the radio (that and two free tickets to the Hoppin’ John’s Fiddler’s Convention–it pays to be tuned into WUNC on Saturday nights at 10. Cha-ching!).
This relationship with reading influences my writing style. When I write, I try to keep my readers awake. Not with what I write — I have full faith in the topic at hand’s capacity to speak for itself — but with the way I write it.
My past experience writing for a published paper was in high school, where I spent four years as co-editor of the “Hustle and Bustle” page. I authored a satirical advice column in which troubled high schoolers (me) could send their personal woes to someone who would publish them for the whole school to read (also me). I like writing as a secondary form of chatting.
My senior year, I retitled my column “Dear Addy,” after the well-known advice column “Dear Abby.”
And so it is with this laudable writing background that I report to you on the groundbreaking discoveries from one of the top research universities in the U.S.
Why write for a research blog? Research is interesting. Research makes the world go round. Just ask a freshman. They all came here for the “research opportunities,” as did all the other freshmen at all the other universities.
Before I sign off, I will let you know where you might catch me in my free time. This is a key element of the standard student bio, and I am prone to severe FOMO, so let me get right to it.
I am a sophomore from Hickory, North Carolina hoping to major in Public Policy and minor in Math. In my free time you might catch me listening to NPR, jogging, potting, singing to myself, making a smoothie, telling people about my smoothie, spamming my contacts for an ice cream date, or for the not-so-lucky, trying my best at Appalachian-style fiddle.
When I write about myself, it always reads like a poorly crafted match.com zinger. Boring, awkward, and something along the lines of:
I’m Alex. Aquarius. Love dogs, classic rock, old NCIS episodes. $1 Goodwill paperback thrillers, marked with “Happiest 53rd Richard! All my love, Janet” and “8/17/2005, Saw this and thought of you!” And I like to ask myself why Steven King’s Carrie conjures up thoughts of said person? Who’s Richard? How’s Janet?
I also love coffee. And tea. Peppermint, of course. Irish breakfast, sure. Chamomile, why not. But I think I really just like collecting mugs — hearty ceramics, dainty porcelain, hand-painted, non-dishwashable, chipped, stained monstrosities. It might be a problem though (as I don’t have much shelf space).
Favorite genre of film? It’s got to be anything in the Meg Ryan romcom cinematic universe. Or the Brat Pack coming-of-age cannon. Breakfast Club, St. Elmo’s Fire, About Last Night, Pretty in Pink. Really just the Judd Nelson je ne sais quoi.
My dog and I celebrating her 11th birthday this summer!
I think my 2nd grade superlative was “Wormiest Bookworm,” whatever that means. That might’ve been the year I read every Nancy Drew book in the library and founded the neighborhood’s first and only detective business. I do wish I could say I’ve Jules Verne’d the world in 80 days — circumnavigating all five nebulous oceans, frozen Arctic plains, Swiss peaks, and continental slopes; Phileas Fogging my way through the Mediterranean, aperitivo in hand. But I’m a bit unworldly in the geographic sense. I’ve only been out of the country once to boat up next to Niagara Falls, wearing a thin, plastic poncho and an I <3 Canada tee (though I’ve possibly made it a second time to Canada after getting lost on the circumference of a lake in Vermont).
I’ve only ever lived in Charleston, SC, never straying too far from its labyrinth of intercostals and waterways, its Theseus-like shrimpers, gliding into port. At Duke, I spend half my time majoring in molecular/cellular biology and the other lamenting my landlockedness, missing Charleston’s temperate sea breeze.
Beach in the middle of winter
Growing up there was all briny inlet and Waffle House, midnight bacon, butter pats, cordgrass, molting blue crab, churches on every street corner and in every denomination, weak coffee and greasy hash brown breakfast, September hurricanes, salt, cicadas, farm stands packed with peaches, a once-in-a-hundred year 6-inch snowfall that closed school for two weeks.
On Saturdays, I sharktooth-hunted with my sisters in pluff mud plots now developed (strangers tend to find the smell of the marsh pungent, but I think it’s character building). Fished for red drum. Searched for pearls in half-mooned oyster mouths. Kayaked down creeks.
Charleston’s a literary city, or so I’ve always heard. I think Edgar Allen Poe’s ghost haunts a cobble-stoned alley downtown or something like that. And if not an alley then a quaint B&B, its porch bearing creaky rocking chairs and purple coneflower. I went to an arts-specialized middle and high school for creative writing, wrote some bad poetry in my formative years and a couple of questionable short films, then went to college and somehow fell into the field of cell bio and now I spend a decent chunk of my free time researching genetic heart disease in a campus lab. Feeding cardiomyocytes via gentle pipette like they’re sea monkeys.
I like to picture the act of writing and that of science as similar — fraternal twins or first cousins — and I don’t think it a coincidence that early philosophers were our first physicians, mathematicians, physicists, chemists, etc. Both fields challenge us to pose questions about our world, about its inhabitants, its oddities, its nuances. We just go about answering them differently.
For this reason, I’m incredibly excited to join Duke’s Research Blog, to write about science and innovation, to poeticize protein structures or to search for lyricism in neuronal action potentials the way a deep sea troller searches for the elusive giant squid. I just think there’s something so wonderful about learning new things, cradling little curiosities that often lead nowhere, and doing so through an accessible, enjoyable medium.
