Biomedical engineering. Climate science. Political science. Global Health.
While these departments are housed in buildings far from each other on campus, their current research was all spotlighted at the Duke Undergraduate Research Symposium on April 10. Over the course of two hours, 120 budding researchers presented their work in Penn Pavilion, eagerly chatting with peers, faculty, and community members alike.

The level of professionalism was obvious upon a glance at the poster titles. The symposium was strongly represented by the biomedical and health sciences; hence, membrane receptors and transport proteins bearing combinations of letters and numbers populated the majority of posters. However, many projects shared findings unrelated to enzymes or transgenic models: posters investigating “The Undocumented Republican Latino Vote” and “Palimpsest and Identity in Hong Kong” attracted as much attention.
I began my journey by talking to Eduardo Fadul Chavez, a junior who is researching chemistry. He gave me an invigorating talk on Nedd4 E3 ligase ligands (a field I admittedly have no background knowledge in). What was greatly appealing about his presentation was his focus on the relevance and impact of his team’s work, especially in innovating treatments for Parkinson’s and other cancers. “Yes, we hope to apply our findings from a pharmacological perspective,” Chavez said. “Nedd4 plays an important role in Parkinson’s disease, so figuring out how to inhibit its activity can greatly inform therapeutic development.”

After this inspiring talk aiming to improve health and cure ailments from a biological perspective, I wandered around in search of a project looking into the sociocultural perspective. Walking across the room, I encountered Austin Brown and his colleagues presenting their work with the Help Desk.
“The Help Desk is a student-led initiative seeking to tackle social determinants of health,” Brown told me. The organization began as a Bass Connections project and has since attracted hundreds of student volunteers. Currently, about 50 volunteers work across three sites: the Duke Hospital Emergency Department, the Duke Endocrinology Clinic, and the Lincoln Community Health Center. “If patients screen positive on the background survey provided, our community resource navigators will provide support by connecting them with local organizations and follow up after the appointment to ensure they are doing well.”
The Help Desk has reached more than 3,200 patients since its inception, Brown said. Maintaining communication with patients after the initial meeting or appointment can be tricky, however. “Our biggest barrier is retention and keeping the channels of contact open,” Brown said.
By this point, I was already amazed by the depth and impact of my peers’ research. I was only more impressed when I came across the poster of Millie Evonlah, who presented on the impact of paternal cannabis consumption on adolescent offspring glutamatergic and cholinergic systems. Given the rise in recreational marijuana usage and legalization, there is a great need to study the impact of men’s usage, particularly intermittent usage, on their children’s brain regions regulating immune and cognitive function.

“We hypothesized that there would be different expression results and responses between male and female offspring,” Evonlah said, “and our findings support this claim.” While there was decreased glutamatergic expression in the CA3 hippocampal region in both male and female offspring, males and females experienced increased acetylcholine expression in different brain regions. Additionally, only the “weekenders,” or animal subjects who partook in intermittent cannabis exposure, imparted significant biological alterations in their offspring’s brains.
All these presentations were inspiring to listen to, and selecting the few to cover in detail was a difficult task. However, I would be amiss not to mention a few other invigorating presentations I listened to. For instance, Michael Wang, who studied GRK-2 mediated regulation of brain-derived neurotrophic factor in the ischemic heart, and I had a lengthy conversation about daily research activities and cell culturing principles. I also had a spirited discussion with Madeline Morrison and her co-presenters, who talked about their experiences conducting fieldwork in Roatán, Honduras, and their perspectives on the importance of global health research.
After two hours of interacting with student researchers, it was clear to me that Duke’s research efforts indeed transform, improve, and save lives. The undergraduate student body’s collective desire to pursue scientific discovery, clinical innovation, and sociocultural advancement is a motivating force that cannot be understated.
In this season, let us all spring into research!
